Polyarticular juvenile rheumatoid idiopathic arthritis is also identified as Polyarthritis. It is a disease wherein 4 or more joints are affected after 6 months of the infirmity. ibuprofen By the name itself, which includes ‘juvenile’, it merely affects children between 12 and 16 years old. This condition afflicts roughly one out of three patients with juvenile rheumatoid arthritis. It also affects the girls two times more than the boys.
Polyarticular juvenile idiopathic arthritis usually originates in the knees, or hips, which are large joints. However, it can also begin in the hands, fingers, and feet, which are small joints. This type of JIA may also attack the ankles, jaw, and neck. This form of JIA is more harsh and severe than oligoarticular JIA because several joints are afflicted and it gets worse sooner or later.
There are two classifications of Polyarticular JIA. The first is rheumatoid factor-positive (RF-positive), wherein an antibody, named rheumatoid factor, exists in the blood. The second one is rheumatoid factor-negative (RF-negative), wherein the rheumatoid factor does not exist in the blood.
The polyarticular JIA damages joints symmetrically on the left and right sides of the body. A person with polyarthritis may also acquire joint damages or erosion and systemic symptoms like fever, rashes, and body weakness. He or she may also develop rheumatoid nodules, which are small bumps in the skin, particularly at the elbow or heels like pressure point areas. Although, these are most frequent in RF-positive polyarthritis.
In conditions like polyarticular juvenile idiopathic rheumatoid arthritis, it is important to control the inflammatory process that it elicits. To do it, the most conventional way is through rheumatoid arthritis medications. The medications used in this illness are non-steroidal anti-inflammatory drugs (NSAIDs), steroids, and TNF-blockers.
The non-steroidal anti-inflammatory drugs (NSAIDs) are essential to lessen symptoms and halt permanent injuries. These drugs include ibuprofen, naproxen, celecoxib, and etoricoxib among others. For some, only one NSAID is necessary to lessen inflammation. If NSAIDs are not enough, the child may need to take steroids. The most commonly used steroids for polyarticular JIA are prednisone and prednisolone. Steroids gives a quick effect on the body, however, too much use of steroids can lead a child to have weak bones and short stature.
One of the newest medications for polyarticular juvenile idiopathic arthritis is the TNF-blockers. This includes etanercept, infliximab, and meloxicam. These drugs are given to patients with moderate to severely active polyarticular JIA and do not respond to the first-line drugs.
Polyarticular juvenile idiopathic rheumatoid arthritis involves multiple joints than the more common type, the pauciarticular. Some patients have the rheumatoid factor present in their blood, and it can cause to have the disease re-emerge as rheumatoid arthritis when they get older. Luckily, almost all of the patients will be able to outgrow the illness.